Every treatment. One clinic.
Real medicine.
From a real clinic.

ED from $0.76/day · GLP-1s from $96.05/mo — provider-reviewed, typically under 24 hours, free 2-day shipping.
Affinity Direct is the online clinic of Affinity Whole Health — est. 2012, four Midwest locations, 10,000+ patients treated.
Real answers from our AI advisor — a licensed provider makes every medical decision.
As seen & heard on

Trusted By
Thousands Of Patients
Healthcare should be simple, accessible, and personalized. Connect with licensed providers, receive expert guidance, and get the care you need — all from the comfort of home.
Every treatment. One clinic.
Shop By Category
Daily Tadalafil With Auto-Refill
ED Treatment
Sildenafil & Tadalafil
From $0.76/day
Free Cold-Chain Shipping
Weight Loss
Semaglutide & Tirzepatide
From $96.05/mo
Injection Supplies & Shipping Free
Peptide Therapy
Sermorelin · Glutathione · NAD+ · MIC+B12 · PT-141
From $84.76/mo
Subscribe & Save 22%
Supplements
Mood, Vitamin D3, Biotin, Energy, & Sleep
From $39/bottle
How It Works
Everything happens online — from order to your door in as little as 48 hours. No appointments, no video calls, no one to talk to.
[01]
Choose Your Treatment
Pick your treatment and answer a quick 5-minute health intake online — right from your phone. No appointment, no phone call.

[02]
Quick Medical Review
A licensed provider reviews everything online, typically within 24 hours. No video call, no waiting room, no one to talk to.

[03]
Delivered to Your Door
Free 2-day shipping in plain, unmarked packaging — left right at your door. Supplies included when your treatment needs them.

Every treatment. One clinic.
Licensed providers in all 50 states · 4 Midwest clinic locations
Affinity Direct Is Not A Startup. Not An App. A Clinic.
Affinity Direct is backed by Affinity Whole Health: real clinics, real staff, and a reputation built before online checkout.
Talk To A Real Person
Real people pick up
the phone.
Not sure which treatment fits? Our treatment specialists are part of the same team behind our four Midwest clinics — tell them your goals and they’ll point you to the right option, person to person.
FAQ
Frequently Asked Questions
Everything you need to know before getting started
Yes. Affinity Direct is the online division of Affinity Whole Health — a Midwest clinic system with locations in Cleveland, Columbus, Indianapolis, and Chicago. Your prescriptions are reviewed by real, licensed Affinity providers.
Affinity Direct serves patients in all 50 states — ED treatment, peptide therapy, and medical weight loss. Ohio, Indiana, Illinois, Arizona, and Pennsylvania are served directly by the Affinity Whole Health clinic network; every other state is fulfilled through our licensed partner provider network.
No. Across ED treatment, peptide therapy, and supplements you can order one-time without a subscription. Auto-refill plans are available for convenience and savings — but they are never required.
All data is encrypted and handled in full HIPAA compliance. We maintain signed BAA agreements with every third-party service in our stack. We never sell your information.
Affinity Direct is the online extension of Affinity Whole Health, an established clinic group with licensed providers and real clinical infrastructure — offering ED treatment, GLP-1 weight loss, peptide therapy, and daily supplements from one clinic.
Your Health Deserves
Better Care.
Your journey to better health starts with one simple assessment. Get personalized care for weight loss, men's health, sleep, mood, energy, peptides, and everyday wellness.















